Polymethylated phloroglucinol meroterpenoids from Rhodomyrtus tomentosa and their antibacterial and acetylcholinesterase inhibitory effects
Từ khóa
trừu tượng
Rhotomentodiones C-E ( 1 - 3 ), three new polymethylated phloroglucinol meroterpenoids with diverse configurations, were isolated from the twigs and leaves of Rhodomyrtus tomentosa . Their structures and absolute configurations were established mainly by means of comprehensive spectroscopic data and electron circular dichroism (ECD) calculation. Among them, compound 2 exhibited both antibacterial activity with an MIC value of 12.5 μ g/mL against Propionibacterium acnes and AChE inhibitory activity with an IC 50 value of 22.9 μ M.
Keywords: Rhodomyrtus tomentosa, Polymethylated phloroglucinol meroterpenoids, Antibacterial activities, Acetylcholinesterase inhibitory effects.