Exercise Performance

PhytoDyNAmic

Inulin

Applied Bioenergetics Lab at Faculty of Sport and PE

Medium-Term Supplementation With Herbal Extract for Exercise Performance and Antioxidant Status

Does Medium-Term Supplementation With PhytoDyNAmic Affect Exercise Performance and Antioxidant Status in Healthy Men: A Randomized Controlled Trial?

Sergej Ostojic

Professor

University of Novi Sad, Faculty of Sport and Physical Education

Subject will take 10g inulin for 2 weeks, 20g of inulin for the next 2 weeks and then 30g for the remainder of the investigations.

Subjects will take 10g cellulose a day for 2 weeks, followed by 20g a day for 2 weeks, then 30g a day for the rest of the study.

Cellulose

Total

Sex: Female, Male

Race and Ethnicity Not Collected

Region of Enrollment

Weight

Haemoglobin A1c

An oral glucose tolerance test (OGTT) using 75 g of glucose was performed to clarify glycaemic status.

Glycaemic Control

Food intake following intervention over 9 weeks compared to baseline and between the two group

Food Intake in Gram at 9 Weeks

Change in body weight over 9 week intervention

Percentage Change in Body Weight

Overall Study

Prof Gary Frost

Prediabetes

Subjects will have 4 dietary counselling sessions in the first 9 weeks of the study with a goal to lose 5% of their body weight by week 9. They will be asked to maintain their weight loss until week 18.

Subject will take inulin for 6 weeks in total with no other change to their diet or lifestyle.

Subject will take cellulose for 6 weeks in total with no other change to their diet or lifestyle.

Subject will take inulin for 6 weeks in total with no other change to their diet or lifestyle.
Subject will wear a Continuous Glucose Monitor for 4 x 5 days during the study.

Subject will take cellulose for 6 weeks in total with no other change to their diet or lifestyle.
Subject will wear a Continuous Glucose Monitor for 4 x 5 days during the study.

Imperial College London

Effect of Fermentable Carbohydrate on Glucose Homeostasis

Effect of Fermentable Carbohydrate on Glucose Homeostasis and Weight Management in Subjects With Prediabetes

Anonamised data will be shared via a web site

Healthy volunteers will be randomised to receive either placebo capsules PO plus an infusion of normal saline, acetylcysteine capsules PO plus an infusion of normal saline or placebo capsules PO plus an IV infusion of acetylcysteine in normal saline

Volunteers with CKD III will be randomised to receive either placebo capsules PO plus an infusion of normal saline, acetylcysteine capsules PO plus an infusion of normal saline or placebo capsules PO plus an IV infusion of acetylcysteine in normal saline

Healthy volunteers will receive a single IV dose of 100mls Visipaque 320 (iodixanol, equivalent to 320 mg iodine/ml). They will then be randomised to receive either placebo capsules PO plus an infusion of normal saline, acetylcysteine capsules PO plus an infusion of normal saline or placebo capsules PO plus an IV infusion of acetylcysteine in normal saline

Volunteers with CKD III will receive Visipaque 320 during coronary angiography. They will have been randomised to receive either placebo capsules PO plus an infusion of normal saline, acetylcysteine capsules PO plus an infusion of normal saline or placebo capsules PO plus an IV infusion of acetylcysteine in normal saline

Radiocontrast-induced Nephropathy

Participants will receive packs of either 8 placebo capsules or 8 acetylcysteine (600mg) capsules. They will be asked to take 2 tablets at 08.00 and 22.00 on the day before the study and the day of the study. On the day of the study participants will receive an IV infusion of either normal saline or acetylcysteine (200mg/kg)

Acetylcysteine

Visipaque 320

The dose of Visipaque will be administered by the consultant cardiologist performing the coronary angiography

inulin/buồn nôn

Medium-Term Supplementation With Herbal Extract for Exercise Performance and Antioxidant Status

Effect of Fermentable Carbohydrate on Glucose Homeostasis

Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material

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