9 các kết quả
BACKGROUND
The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid malabsorption. One embodiment of the present invention relates to a composition comprising an sn-2 monoacylglycerol derivative,
BACKGROUND
The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid malabsorption. One embodiment of the present invention relates to a composition comprising an sn-2 monoacylglycerol derivative,
BACKGROUND
The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid malabsorption. One embodiment of the present invention relates to a composition comprising an sn-2 monoacylglycerol derivative,
BACKGROUND
Monoacylglycerol lipase (MGLL or MAGL) is an enzyme responsible for hydrolyzing endocannabinoids such as 2-AG (2-arachidonoylglycerol), an arachidonate based lipid, in the nervous system.
SUMMARY OF THE INVENTION
Disclosed herein are methods of treating inflammation or neuropathic pain in
This is a National Phase Application filed under 35 U.S.C. 371 as a national stage of PCT/JP2014/084752, filed Dec. 25, 2014, an application claiming the benefit of Japanese Application No. 2013-269244, filed Dec. 26, 2013, the content of each of which is hereby incorporated by reference in its
BACKGROUND
The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid malabsorption. One embodiment of the present invention relates to a composition comprising an sn-2 monoacylglycerol derivative,
CROSS REFERENCE TO RELATED APPLICATIONS
The present application is a National Stage of International Application No. PCT/EP2012/056080, filed on Apr. 3, 2012, which claims priority to European Patent Application No. 11160929.3, filed Apr. 4, 2011, the entire contents of which are being incorporated
FIELD OF THE INVENTION
The present disclosure relates generally to ureas and carbamates that inhibit FAAG, MAGL or dual FAAH/MAGL, and to the manufacture thereof and uses thereof. For example, the compounds can be used for treating pain, inflammation, neuropathy, neurodegenerative disease, anxiety
BACKGROUND
Cannabinoid receptors, CB1 and CB2, are part of the endocannabinoid system (ECS), which consists of cannabinoid receptors, endogenous endocannabinoids anandamide (AEA) and 2-arachindonoylglycerol (2-AG) and the hydrolytic enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol