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ADDITIONAL DISCLOSURES
Additional disclosures relating to the instant application may be found in "Compositions And Methods Of Use Of Phorbol Esters" U.S. patent application Ser. No. 12/023,753, filed Jan. 31, 2008, to Richard L. Chang, et al, which claims priority benefit of U.S. Provisional Patent
ADDITIONAL DISCLOSURES
Additional disclosures relating to the instant application may be found in "Compositions And Methods Of Use Of Phorbol Esters" U.S. patent application Ser. No. 12/023,753, filed Jan. 31, 2008, to Richard L. Chang, et al, which claims priority benefit of U.S. Provisional Patent
ADDITIONAL DISCLOSURES
Additional disclosures relating to the instant application may be found in "Compositions And Methods Of Use Of Phorbol Esters" U.S. patent application Ser. No. 12/023,753, filed Jan. 31, 2008, to Richard L. Chang, et al, which claims priority benefit of U.S. Provisional Patent
BRIEF DESCRIPTION OF THE INVENTION
The invention relates to treating neoplastic disease such as leukemia and increasing the white blood cell counts in patients suffering from neoplastic diseases or undergoing chemotherapy by a method which comprises administering parenterally to patients an
2. TECHNICAL FIELD
The present disclosure relates to analogs and derivatives of phorbol compounds, their synthesis, and methods of using the compounds.
3. BACKGROUND
While highly active antiretroviral therapy (HAART) is helping many people with HIV/AIDS live longer, healthier lives, these
2. TECHNICAL FIELD
The present disclosure relates to analogs and derivatives of phorbol compounds, their synthesis, and methods of using the compounds.
3. BACKGROUND
While highly active antiretroviral therapy (HAART) is helping many people with HIV/AIDS live longer, healthier lives, these
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a method of inhibiting protein kinase C function and to compounds and compositions suitable for use in such a method.
2. Background Information
In mouse skin, phorbol esters exert tumor promoting, inflammatory,
FIELD OF THE INVENTION
The present invention relates to a method of treating a solid tumor, and in particular, to a method involving hypoxic stress as one component and protein kinase C activation as another component.
REFERENCES
Cook, P. F., et al., Biochem. 21: 5794-5799 (1982).
Culver, K., et
TECHNICAL FIELD
The present invention relates generally to the medicinal use of phorbol esters.
BACKGROUND
Plants have historically served many medicinal purposes. The World Health Organization (WHO) estimates that 4 billion people, 80% of the world population, presently use herbal medicine for some
TECHNICAL FIELD
The present invention relates generally to the medicinal use of phorbol esters.
BACKGROUND
Plants have historically served many medicinal purposes. The World Health Organization (WHO) estimates that 4 billion people, 80% of the world population, presently use herbal medicine for some
TECHNICAL FIELD
The present invention relates generally to the medicinal use of phorbol esters.
BACKGROUND
Plants have historically served many medicinal purposes. The World Health Organization (WHO) estimates that 4 billion people, 80% of the world population, presently use herbal medicine for some
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is directed to chemical compounds and methods useful in the regulation of thrombin receptor mediated cell stimulation. More specifically, the invention is directed to prothrombin-derived peptides and methods which employ
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is directed to chemical compounds and methods useful in the regulation of thrombin receptor mediated cell stimulation. More specifically, the invention is directed to prothrombin-derived peptides and methods which employ
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is directed to chemical compounds and methods useful in the regulation of thrombin receptor mediated cell stimulation. More specifically, the invention is directed to prothrombin-derived peptides and methods which employ
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a method of inhibiting protein kinase C function and to compounds and compositions suitable for use in such a method.
2. Background Information
In mouse skin, phorbol esters exert tumor promoting, inflammatory,