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TECHNICAL FIELD OF INVENTION
This invention relates to combinations and methods for the treatment of malignant and non-malignant diseases. More particularly, this invention relates to combinations of natural or recombinant tumor necrosis factors ("TNF") and non-steroidal anti-inflammatory agents,
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to methods for inhibiting cyclooxygenase-2 (COX-2) and tumor necrosis factor alpha (TNF.alpha.) activities and treating disorders and diseases associated with elevated COX-2 and TNF.alpha. activities.
2. Description
This application is a National Stage under 35 U.S.C. .sctn.371 of PCT International Application No. PCT/HR03/00026, filed May 20, 2003, which claims the benefit under 35 U.S.C. .sctn.119(e) of prior Croatian Application No. P20020440A, filed May 21, 2002, the entire contents of which are
This application is a National Stage under 35 U.S.C. .sctn.371 of PCT International Application No. PCT/HR03/00022, filed May 20, 2003, which claims the benefit under 35 U.S.C. .sctn.119(e) of prior Croatian Application No. P20020452A, filed May 23, 2002, the entire contents of which are
TECHNICAL FIELD
The present invention relates to compounds of 2-thia-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour
TECHNICAL FIELD
The present invention relates to benzonaphthoazulene derivatives of tiophene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of
FIELD OF THE INVENTION
This invention relates to novel compounds obtained by fermentation of Myxobacteria strain (PM0670013/MTCC 5570). The present invention further relates to the processes for the production of the novel anti-inflammatory compounds, to the culture no. PM0670013 (MTCC 5570), and to
DESCRIPTION
BACKGROUND OF THE INVENTION
The present invention provides a new use for some known compounds. More particularly, the present invention provides a method for preventing renal papillary necrosis induced by non-steroidal anti-inflammatory compounds (NOSAC) by the administration of certain
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a 371 of PCT/KR2010/003239, filed on May 24, 2010, which claims the benefit of Korean Patent Application Nos. 10-2009-0044900, filed on May 22, 2009, and 10-2010-0029016, filed on Mar. 31, 2010, the contents of each of which are
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
TECHNICAL FIELD OF THE INVENTION
The invention relates to aromatic heterocyclic compounds which inhibit the release of inflammatory cytokines such as interleukin- 1 and tumor necrosis factor from cells and are thus useful for treating diseases and pathological conditions involving inflammation such
TECHNICAL FIELD OF THE INVENTION
The invention relates to aromatic heterocyclic compounds which inhibit the release of inflammatory cytokines such as interleukin-1 and tumor necrosis factor from cells and are thus useful for treating diseases and pathological conditions involving inflammation such
TECHNICAL FIELD OF THE INVENTION
The invention relates to aromatic heterocyclic compounds which inhibit the release of inflammatory cytokines such as interleukin-1 and tumor necrosis factor from cells and are thus useful for treating diseases and pathological conditions involving inflammation such
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to Tumor Necrosis Factor Receptor Super Family 25 (TNFR25) agonists, immunotoxins, antagonists and their use in treating cancer, inflammation and effecting immunosuppression, respectively.
2. Background
Many disorders of