A unique class of anti-neoplastic compositions are described. The compositions contain certain Chinese medicinal herbs: Panax ginsing, Poria cocos, Atractylodes macrocephala, Angelic sinensis, Astragalus membranaceus, Curcuma zedoaria, Scutellaria baicalensis, Coptis chinenisis, Glycyrrhiza uralenisis, Crataegus pinatifida, Hordeum vulgare, Schisandra chinensis, Hedyotis diffusa, Ophiophogon japonicus, and Lobelia chinesis lour. Extensive testing indicates an effective treatment rate of 69.7% and 84.3% when used in combination with radiotherapy or chemotherapy. The animal trials conducted demonstrate that the anti-neoplastic compositions increase the activity of NK cells, and reduce and prevent metastasis of tumors under stress conditions.

Anti-neoplastic drug

A preparation comprises a herbal extract and/or fraction, and a pharmaceutical preparation includes extract of Curcuma mangga Val. et Zipp., which has bioactivities in reducing expression levels of 5-alpha-reductase-1, androgen receptor, and PI3 in prostate cancer cells. The use of this present invention is directed to reduce prostate enlargement. Moreover, it also can be used to treat prostate cancer, lung cancer, and other diseases related to GPCR pathway.

PT DEXA MEDICA

PT Dexa Medica

Curcuma mangga val et. zipp. extract as a treatment to overcome prostate problems

The invention concerns carbon dioxide extracts of Curcuma amada (mango ginger), including supercritical carbon dioxide extracts of C. amada; methods for their production; compositions comprising the extracts; methods for treating or delaying the onset of conditions such as cell proliferation disorder (e.g., cancer), inflammation, infection, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, platelet hyper-aggregation, immune disorder such as autoimmune disorder, or neurodegenerative condition; and methods for inhibiting expression of Bcl-2, Bak, and p53 genes; inhibiting expression of the COX-2 and NF-kB genes, inhibiting production of phosphorylated target of rapamycin (TOR), modulating AMP-activated protein kinase (AMPK), inhibiting protein kinase B (AKT) signaling, modulating the Ras/Raf/MEK/ERK signaling pathway, and modulating the Ras/PI3K/PTEN/Akt/mTOR signaling pathway. Another aspect of the invention concerns a method for inhibiting contamination, comprising applying the extract or composition of the invention to a surface. Another aspect of the invention concerns a method for promoting longevity of a cell in vitro or in vivo, comprising contacting a target cell in vitro or in vivo with an effective amount of the extract or composition of the invention. Another aspect of the invention concerns a method for promoting longevity of a subject, comprising administering an effective amount of the extract or composition of the invention. Another aspect of the invention concerns a method for inhibiting the metabolism of a cancer cell, comprising contacting the target cancer cell in vitro or in vivo with an effective amount of the extract or composition of the invention. Another aspect of the invention concerns a kit including the extract or composition; a container containing the extract or composition; and packaging material.

DHARMA BIOMEDICAL, LLC

FLAVEX NATUREXTRAKTE GMBH

Extracts of Curcuma amada and uses thereof

A therapeutic herbal composition is beneficial for enhancing the immune system and treating such a diverse range of diseases as cancer, AIDS, Epstein Barr syndrome and depression. It is also useful as a general blood tonic. This composition includes the synergistic combination of Boswelia carterii stem resin, Styrax benzoin stem resin, Cinnamomum zeylanicum bark, Curcuma zedoaria root, Syzygium aromaticum fruit, Nardostachys chinensis root, Betula alba bark, Impatiens balsamina bark, Costus spicatus root, Allilum sativum bulb and Cyperus rotundus root.

curcuma/neoplasms

Anti-neoplastic drug

Curcuma mangga val et. zipp. extract as a treatment to overcome prostate problems

Extracts of Curcuma amada and uses thereof

Herbal composition and method of treating HIV infection

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