7 結果
This application is a 371 of PCT/JP93/01589 filed Nov. 4, 1993.
1. Technical Field
The present invention relates to novel 2-alkoxy-5,6,7,8-tetrahydroquinoxaline derivatives, a production method thereof, and a pharmaceutical use thereof. The 2-alkoxy-5,6,7,8-tetrahydroquinoxaline derivatives are
The invention relates to tetrahydropyridinyldibenzazepine derivatives of formula I ##STR2## wherein R.sub.1 is a substituent selected from the group consisting of hydrogen, halogen, and lower alkyl;
R.sub.2 is selected from hydrogen, and unsubstituted or hydroxy substituted lower alkyl or lower
BACKGROUND OF THE INVENTION
Morphine or other bimodally-acting opioid agonists are administered to relieve severe pain due to the fact that they have analgesic effects mediated by their activation of inhibitory opioid receptors on nociceptive neurons (see North, Trends Neurosci., Vol. 9, pp. 114-117
FIELD OF THE INVENTION
The present invention relates to a "stewardess" composition suitable for the prevention of disadvantageous physiological symptoms occurring during unusual external movement (such as transportation) of healthy humans and mammal animals containing a compound of the general
FIELD OF THE INVENTION
This invention relates to new therapeutic uses of tramadol and its structural and/or functional analogues, and to new formulations thereof.
BACKGROUND OF THE INVENTION
Tramadol has the chemical name (+/-)-trans (RR,SS)-2-[(di-methylamino)methyl]-1-(3-methoxyphenyl)
The present Invention is directed to a composition and method which assists tobacco users in breaking the habit. While portions of this Specification may be expressly directed to smoking, it is to be understood that the method and composition set forth herein are applicable to other forms of tobacco
TECHNICAL FIELD
This invention relates to substituted benzimidazolone derivatives which are useful in the field of pharmaceuticals. More specifically, the invention relates to substituted benzimidazolone derivatives exhibiting selective antagonist activities against muscarinic acetylcholine receptor