fibrosis/triglyceride

FIELD OF THE INVENTION The present invention relates to methods of prevention, treatment or alleviation of cachexia and other wasting syndromes or conditions of loss of weight and/or muscle atrophy by modulation, including inhibition, of lipase, particularly adipose triglyceride lipase (ATGL). The

This application is a 371 of PCT/JP92/01486 filed Nov. 13, 1992. TECHNOLOGICAL FIELD The present invention relates to a drug for hepatic diseases, especially an ameliorant for hepatic function and a drug for hepatitis, which contains docosahexaenoic acid as the active ingredient. BACKGROUND

CROSS-REFERENCE TO RELATED APPLICATIONS This application is a 371 U.S. National Stage of International Application No. PCT/AU2013/001310, filed Nov. 13, 2013. This application claims the benefit of Australian Patent Applications Nos. 2012904937, filed Nov. 13, 2012 and 2012905406, filed Dec. 11,

TECHNICAL FIELD The present invention relates to a novel liver fat accumulation inhibitory composition, a food additive for liver fat accumulation inhibition, and a method of inhibiting liver fat accumulation. BACKGROUND ART It has been considered that fatty liver, which is a disease wherein fat is

This application is a .sctn.371 national phase filing of PCT/NL2005/000813 filed Nov. 25, 2005; and claims priority to three European applications: EP 04 078265.8 filed Nov. 30, 2004; and EP 05 075856.4 filed Apr. 12, 2005; and EP 05 077029.6 filed Sep. 6, 2005. TECHNICAL FIELD The invention relates

FIELD OF THE INVENTION The present invention relates to protection against renal failure progression in chronic kidney diseases. This includes the treatment of kidney diseases associated with nephrectomy, renal fibrosis, glomerular sclerosis, and end-stage renal disease. This also includes

FIELD OF THE INVENTION The present invention is directed towards novel prodrugs of alcohol, amine, and thiol-containing compounds, to their preparation, to their synthetic intermediates, and to their uses. Prodrugs of the invention may be used to deliver drugs to the liver with high tissue

FIELD OF THE INVENTION The present invention is directed towards novel prodrugs of alcohol, amine, and thiol-containing compounds, to their preparation, to their synthetic intermediates, and to their uses. Prodrugs of the invention may be used to deliver drugs to the liver with high tissue

SUMMARY OF THE INVENTION The present invention relates to obeticholic acid, an agonist for FXR, processes of preparation for obeticholic acid, pharmaceutical formulations comprising obeticholic acid, and the therapeutic use of the same. ##STR00002## The present invention relates to a crystalline

SUMMARY OF THE INVENTION The present invention relates to obeticholic acid, an agonist for FXR, processes of preparation for obeticholic acid, pharmaceutical formulations comprising obeticholic acid, and the therapeutic use of the same. ##STR00002## The present invention relates to a crystalline

SUMMARY OF THE INVENTION The present invention relates to obeticholic acid, an agonist for FXR, processes of preparation for obeticholic acid, pharmaceutical formulations comprising obeticholic acid, and the therapeutic use of the same. ##STR00002## The present invention relates to a crystalline

SUMMARY OF THE INVENTION The present invention relates to obeticholic acid, an agonist for FXR, processes of preparation for obeticholic acid, pharmaceutical formulations comprising obeticholic acid, and the therapeutic use of the same ##STR00002## The present invention relates to a crystalline

SUMMARY OF THE INVENTION The present invention relates to obeticholic acid, an agonist for FXR, processes of preparation for obeticholic acid, pharmaceutical formulations comprising obeticholic acid, and the therapeutic use of the same. ##STR00002## The present invention relates to a crystalline

SUMMARY OF THE INVENTION The present invention relates to obeticholic acid, an agonist for FXR, processes of preparation for obeticholic acid, pharmaceutical formulations comprising obeticholic acid, and the therapeutic use of the same. ##STR00002## The present invention relates to a process for the

FIELD OF INVENTION This invention relates to novel compounds which are inhibitors of acyl coenzyme A: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination with weight