Journal of Pharmacy and Pharmacology 1984-Nov
Anti-inflammatory action of drugs that raise adenosine-3',5'-cyclic monophosphate and putrescine levels in-vivo.
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Isoprenaline and salbutamol, two beta-adrenoceptor agonist drugs, and 3-isobutyl-methyl xanthine and thioacetamide have been shown to be anti-inflammatory. Their mode of action is probably due to an increase in the levels of the three endogenous substances adenosine-3',5'-cyclic monophosphate and putrescine and spermidine in-vivo.