The group contains healthy individuals with chronic periodontitis who will receive Normal Saline as placebo

The group contains healthy individuals with chronic periodontitis who will receive Nigella sativa Oil as intervention

Chronic Periodontitis

The individuals will apply 55 drops of Nigella sativa Oil on gingivae twice daily for two weeks

Nigella Sativa Oil

The individuals will apply 55 drops of Normal saline on gingivae twice daily for two weeks

Normal saline

Fatima Memorial Hospital

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis Before and After Treatment With Nigella Sativa (Kalonji) Oil

These inflammatory marker will be measured in patients saliva again after 2 weeks. There will be reduction in their levels.

Data sharing will be considered after the completion of studies

Dr. Ghazala Hassan

Research Scholar

University of Health Sciences Lahore

Healthy Individuals with Chronic Periodontitis Only

Scaling and root planing (SRP) followed by placebo gel local drug delivery

Oral prophylaxis followed by placement of placebo gel

placebo

Oral prophylaxis followed by placement of Alendronate gel

Alendronate

Oral prophylaxis followed by placement of Aloe Vera gel

Aloe Vera

Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis

1% Alendronate and Aloevera Gel Local Host Modulating Agents in Chronic Periodontitis Subjects With Class II Furcation Defects: A Randomized Controlled Clinical Trial

Dr. A R Pradeep

Professor and HOD, Dept of Periodontology

Government Dental College and Research Institute, Bangalore

Tooth brushing with dentifrice and standardized tooth brush

Tooth brushing with dentifrice and standardized tooth brush followed by massaging with aloe vera gel

Scaling and root planning was done with ultrasonic scalar. It was followed by aloe vera massaging on half arch for 3 minutes daily

CHRONIC PERIODONTITIS

Tooth Brushing with Dentifrice Tooth Brushing with Dentifrice (Standard Tooth Brushing technique will be demonstrated by using same type of tooth brush and toothpaste).

Tooth Brushing

Tooth Brushing with Dentifrice (with same type of tooth brush and toothpaste) and massaging with aloe vera gel

aloe vera Massaging

on one side of the arch only Scaling and Root Planing(SRP) to be done, while on the other side, after the Scaling and Root Planing massaging with aloe vera ge; shall be carried out by the patients/subjects

aloe microdonta/antibakterial

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis

Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis

Efficacy of AloeVera Gel Gum Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients

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