Subcutaneous adipose tissue, serum, plasma, ''buffycoat'', erytrocytes and urine is stored in nitrogen vapour at the biobank of the Diet, Cancer and Health cohort study. Also, whole blood in filter paper and toenail clippings has been stored within the biobank.

Acute Myocardial Infarction

Ischemic Stroke

Peripheral Artery Disease

Exposure to dietary intake of alpha-linolenic acid (ALA) will be assessed using a detailed food frequency questionaire filled in by participants included in the Diet, Cancer and Health cohort at baseline. Exposure to adipose tissue content of ALA will be determined by gas chromatography in all incident cases and in subcohort of 3500 participants randomly drawn from the total cohort.

Alpha-linolenic acid

Alpha-linolenic Acid and the Risk of ASCVD

Alpha-linolenic Acid and the Risk of Atherosclerotic Cardiovascular Disease

Christian Sørensen Bork

Dr. Christian Sørensen Bork

Aalborg University Hospital

Danish Heart Foundation

Margarine spread that yields 400 mg of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA) per day for average margarine use of 20 grams per day

Margarine spread that yields 2 grams of alpha-linolenic acid (ALA) per day for average margarine use of 20 grams per day

Margarine spread that yields 400 mg of EPA + DHA per day plus 2 grams of ALA per day, for average margarine use of 20 grams per day

Margarine spread that contains no EPA, DHA or ALA (exchanged for oleic acid)

Cardiovascular Diseases

Daily use of margarine spread (approximately 20 grams) during 40 months

margarine spread

Information site of the Alpha Omega Trial; statistical analysis plans are posted here

Wageningen University and Research Centre

Division of Human Nutrition, Wageningen University, The Netherlands

The Graduate School VLAG, Wageningen, The Netherlands

Medisch Centrum Alkmaar

Flevo Ziekenhuis

Meander Medisch Centrum

Sint Lucas Andreas Ziekenhuis

BovenIJ Ziekenhuis

Slotervaartziekenhuis

Gelre ziekenhuizen

Lievensberg Ziekenhuis

Rode Kruis Ziekenhuis

IJsselland Ziekenhuis

Ziekenhuis Gelderse Vallei

Catharina Ziekenhuis

Medisch Spectrum Twente

St. Anna Ziekenhuis

Oosterscheldeziekenhuis

Ziekenhuis Hilversum

Diaconessenhuis

Rijnland Ziekenhuis

Sint Antonius Ziekenhuis

Canisius Wilhelmina Ziekenhuis

Erasmus MC

Havenziekenhuis

Haga Ziekenhuis, location Leyweg

Bronovo Ziekenhuis

Haga Ziekenhuis, location Sportlaan

Twee Steden Ziekenhuis

Maxima Medisch Centrum

Alysis Ziekenhuis

Wageningen University, Division of Human Nutrition

Zaans Medisch Centrum

't Lange Land ziekenhuis

Isala Klinieken

Alpha Omega Trial: Study of Omega-3 Fatty Acids and Coronary Mortality

Alpha Omega Trial: A Randomised, Placebo Controlled, Double Blind Intervention Study of the Effect of Low Doses of Omega-3 Fatty Acids on Cardiovascular Diseases in Patients With a History of Myocardial Infarction

linolenic acid/infarction

Alpha-linolenic Acid and the Risk of ASCVD

Alpha Omega Trial: Study of Omega-3 Fatty Acids and Coronary Mortality

Dietary Fatty Acids, PPAR Activated Genes, and CHD

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