Panax ginseng 400 mg by mouth twice a day from Day 1-29 for first 30 participants in Part 1. Completion of questionnaires taking about 30 minutes on Day 15 (± 3 days), Day 29 (± 3 days), and Day 57 (± 3 days), regarding symptoms such as fatigue, mood, depression, anxiety, nausea, appetite problems, sleep problems, and overall sense of well-being.

Panax ginseng 400 mg by mouth twice a day from Day 1-29. Completion of questionnaires taking about 30 minutes on Day 15 (± 3 days), Day 29 (± 3 days), and Day 57 (± 3 days), regarding symptoms such as fatigue, mood, depression, anxiety, nausea, appetite problems, sleep problems, and overall sense of well-being.

Oral placebo twice daily for 4 weeks. Completion of questionnaires taking about 30 minutes on Day 15 (± 3 days), Day 29 (± 3 days), and Day 57 (± 3 days), regarding symptoms such as fatigue, mood, depression, anxiety, nausea, appetite problems, sleep problems, and overall sense of well-being.

Advanced Cancers

Solid Tumors

400 mg by mouth twice daily from Day 1-29.

Panax Ginseng

Placebo by mouth twice daily for 4 weeks.

Placebo

Completion of questionnaires taking about 30 minutes on Day 15 (± 3 days), Day 29 (± 3 days), and Day 57 (± 3 days), regarding symptoms such as fatigue, mood, depression, anxiety, nausea, appetite problems, sleep problems, and overall sense of well-being.

Questionnaires

University of Texas MD Anderson Cancer Center Website

University of Texas MD Anderson Cancer Center

The Effects of Ginseng on Cancer-Related Fatigue

Fatigue assessment measured by the Functional Assessment of Cancer Therapy- Fatigue (FACIT-F) subscale where rate fatigue on a numerical scale during the previous 24 hours as >/= 4 on a 0 to 10 scale (0 = no fatigue and 10 = worst possible fatigue).

M.D. Anderson Cancer Center

Indena S.p.A

Memory

Learning

Attention

Cognition

Well-Being

HT1001 extract of Panax quinquefolius L

Cognitive, Emotional, Physical and Psychosocial Effects of Panax Quinquefolius L

Cognitive, Emotional, Physical, and Psychosocial Effects of Three Weeks' Prospective Double-Blind Placebo Controlled Cross-Over Exposure to Panax Quinquefolius L (REMEMBER-fX), With Optional Six Months' Open Label Follow-up

panax trifolius/nausea

The Effects of Ginseng on Cancer-Related Fatigue

Cognitive, Emotional, Physical and Psychosocial Effects of Panax Quinquefolius L

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