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Among 647 patent diabetics regularly followed who attended the out-patient clinic of a hospital Diabetology Department between December 1st, 1979 and June 30th, 1980, 35% were habitual smokers, 20% ex-smokers and 45% non-smokers. Insulin-treated diabetics did not smoke more than non insulin-treated
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BACKGROUND
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease associated with multiple macro and microvascular complications, diabetic retinopathy (DR) being the commonest one. Recent literature has reported an increased risk of DR with insulin use.
METHODS
We carried out a
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OBJECTIVE
To investigate the effects of nicotine on retinal alterations in early-stage diabetes in an established rodent model.
METHODS
Sprague-Dawley rats were examined using a combination of confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography to determine
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OBJECTIVE
To establish the prevalence, severity, and risk factors for diabetic retinopathy in a representative sample of Victorian residents aged 40 years and older.
METHODS
A population based, cluster sampling method was used to recruit 4744 participants (86% participation rate). Nine randomly
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A sample of 181 diabetics with diabetic retinopathy was statistically investigated with regard to association of smoking with proliferative retinopathy. The numbers of patients with proliferative retinopathy rose with increasing tobacco consumption. In non-smokers no association existed between
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OBJECTIVE
We explore the influence of lifestyle on the progression of retinopathy.
METHODS
Post hoc statistical analysis.
METHODS
One thousand forty-one patients with type 1 diabetes from 29 specialty clinics.
METHODS
The Diabetes Control and Complications Trial (DCCT) lifestyle data (diet,
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OBJECTIVE
To undertake a systematic review of the literature on the effect of environmental tobacco smoke (ETS) and eye disease.
METHODS
Medline (1950-January Week 2 2007), EMBASE (1980 to 2007 Week 07), SCOPUS and Science Direct were searched on ETS exposure and eye disease using various
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Angiogenesis, the formation of new blood vessels from pre-existing ones, is regulated by the balance between angiogenic activating and inhibiting factors. Recent evidence indicates that nicotine, an alkaloid compound, presents pro-angiogenic effects in certain concentrations. Nicotine-induced
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BACKGROUND
The aims of this study were to estimate the risk for diabetic retinopathy (DR) and to identify risk factors. We investigated a nationwide population-based cohort with diabetes diagnosed at age 15-34years.
METHODS
Of 794 patients registered 1987-1988 in the Diabetes Incidence Study in
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More than 1 billion world's population actively smokes tobacco containing the bioactive component nicotine (NT). The biological role of this molecule is mediated through the activation of nicotinic cholinergic receptors, widely distributed in various human tissues including retinal pigmented
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Smoking is a serious public health problem worldwide. Some authors refer to it as the "silent epidemic of the 20th century." It constitutes an important risk factor for ocular pathologies such as age-related macular degeneration (ARMD), diabetic retinopathy, and neuropathy because the
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We present the results of a population based survey designed to estimate the prevalence and clinical characteristics of carotid artery atherosclerosis (CAS) diagnosed using vascular ultrasonography (VUS) in a low income area of Mexico City encompassing six neighborhoods that we previously studied.
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There are several methods of quantifying the vascularization of tissues, including the skin, but they are imprecise in terms of quantification of the complexity and structure of vascular networks. Fractal analysis can quantify the complexity of any structure existing in nature by using fractional
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This review of recent articles on ocular toxicology concentrates on undesirable effects on the eye induced by systemically used xenobiotics. These effects include the corticosteroid-induced glaucoma and cataracts (especially in children), chloroquine-induced heart block and retinopathy, its possible
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