centella virgata/antidepressant

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Evaluation of the anxiolytic and antidepressant effects of asiatic acid, a compound from Gotu kola or Centella asiatica, in the male Sprague Dawley rat.

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Herbal medication use continues to rise and interactions with existing medications propose risks and may have significant effects and consequences on the administration of anesthesia. The purpose of this study was to investigate the anxiolytic and antidepressant effects of asiatic acid and its

Asiaticoside produces an antidepressant‑like effect in a chronic unpredictable mild stress model of depression in mice, involving reversion of inflammation and the PKA/pCREB/BDNF signaling pathway

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Asiaticoside is one of the triterpenoid components found in Centella asiatica that has promising neuroprotective properties. The present study aimed to evaluate the antidepressant‑like properties of asiaticoside and to investigate the possible mechanisms underlying its mode of action using a mouse

Simultaneous interstitial pneumonitis and cardiomyopathy induced by venlafaxine.

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Venlafaxine is a serotonin-norepinephrine reuptake inhibitor used as an antidepressant. Interindividual variability and herb-drug interactions can lead to drug-induced toxicity. We report the case of a 35-year-old female patient diagnosed with synchronous pneumonitis and acute cardiomyopathy

[Effects of total triterpenes of Centella asiatica on the corticosterone levels in serum and contents of monoamine in depression rat brain].

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OBJECTIVE To investigate the possible effect of antidepressant effect of total triterpentes of Centella asiatica. METHODS The corticosterone levels in serum were measured by fluorescence spectroscopy. The contents of monoamine neurotransmitters and their metabolites in rats cortex, hippocamopus and

[Effect of total triterpenes from Centella asiatica on the depression behavior and concentration of amino acid in forced swimming mice].

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OBJECTIVE To evaluate the antidepressant activity of total triterpenes from Centella asiatica in forced swimming test. METHODS Mice were randomly divided into control group, model group and treatment group. The effect of total triterpenes from Centella asiatica on the immobility time in forced

Nerve Protective Effect of Asiaticoside against Ischemia-Hypoxia in Cultured Rat Cortex Neurons.

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BACKGROUND Asiaticoside is one of the main functional components of the natural plant Centella asiatica urban. Studies have reported it has several functions such as anti-depression and nerve cell protection. Asiaticoside can reduce the cerebral infarct size in acute focal cerebral ischemia in a

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