maltase/necrosis

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Aneurysms and vacuolar degeneration of cerebral arteries in late-onset acid maltase deficiency.

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We present a case of late-onset acid maltase deficiency (AMD) with pronounced involvement of the liver and skeletal muscles. In addition, and in contrast to other adult cases of AMD, the case presented here shows CNS pathology with hypodense and hyperintense white matter areas on CT and MRI scans,

Spermine-induced maturation in wistar rat intestine: a cytokine-dependent mechanism.

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OBJECTIVE Polyamines are of great importance in biologic processes such as cell proliferation and differentiation. The ingestion of spermidine or spermine by suckling rats induces the precocious maturation of the small intestine. In a previous article, the authors hypothesized that this phenomenon

Octreotide alleviates obesity by reducing intestinal glucose absorption and inhibiting low-grade inflammation.

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OBJECTIVE To investigate the role of octreotide, a somatostatin (SST) analog with anti-inflammatory effects, on the digestive and absorptive functions of jejunum in rats fed a high-fat diet, as well as its therapeutic prospects for diet-induced obesity. METHODS Rats were divided into three groups

Biochemical, histological and ultrastructural alterations of the alimentary system in the freshwater crab Sinopotamon henanense subchronically exposed to cadmium.

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Cadmium (Cd) is one of the toxic metals in the aquatic environment. We investigated the effects of Cd on the digestive enzymes, antioxidant enzymes, malondialdehyde (MDA) content and morphology of the hepatopancreas and intestine in the freshwater crab Sinopotamon henanense. Crabs were exposed to

Alterations in kidney enzyme pattern in acute hypervitaminosis A.

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The relation of excessive doses of vitamin A with various kidney pathologies is well known however, information concerning the relation of kidney enzyme activity with acute hypervitaminosis A is rather scarce. In this study we describe the kidney enzymatic alterations observed in rats that received

Effect of aflatoxin culture on intestinal function and nutrient loss in laying hens.

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The negative effects of aflatoxins (AFLA) on hepatic necrosis and total tract digestibility of energy, N, and amino acids have been well documented. However, the question remains if this is an effect on nutrient metabolizability alone or an effect on the intestine, or both, resulting in increased

Bioactive compounds in plant materials for the prevention of diabetesand obesity.

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Plant materials have been widely studied for their preventive and therapeutic effects for type 2 diabetes mellitus (T2DM) and obesity. The effect of a plant material arises from its constituents, and the study of these bioactive compounds is important to achieve a deeper understanding of its effect

Transition from parenteral to enteral nutrition induces immediate diet-dependent gut histological and immunological responses in preterm neonates.

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Necrotizing enterocolitis (NEC) in preterm infants develops very rapidly from a mild intolerance to enteral feeding into intestinal mucosal hemorrhage, inflammation, and necrosis. We hypothesized that immediate feeding-induced gut responses precede later clinical NEC symptoms in preterm pigs.

Beneficial effects of cyclosporine and rapamycin in small bowel ischemic injury.

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Gut ischemia has been implicated in the pathogenesis of necrotizing enterocolitis. Cyclosporine A and rapamycin, both potent novel immunosuppressants which act on signal transduction pathways in CD4+ T-cells, could potentially modulate immune/inflammatory cellular reactions involved in tissue

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