mycobacterium avium-intracellulare infection/glutathione

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Inactivation of rat liver cytochrome P450 (P450) by N,N-dimethylformamide and N,N-dimethylacetamide.

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N,N-dimethylformamide (DMF), an organic solvent widely used in industry, is bioactivated by cytochrome P450 (P450) to reactive metabolites which are believed to be responsible for the hepatotoxicity observed in animals and humans. A decrease of the activating enzyme has been reported in rats treated

The novel arsenical darinaparsin is transported by cystine importing systems.

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Darinaparsin (Dar; ZIO-101; S-dimethylarsino-glutathione) is a promising novel organic arsenical currently undergoing clinical studies in various malignancies. Dar consists of dimethylarsenic conjugated to glutathione (GSH). Dar induces more intracellular arsenic accumulation and more cell death

Dimethylacetamide-induced toxic hepatitis in spandex workers: Clinical presentation & treatment outcomes.

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Dimethylacetamide (DMAc) has been reported to induce toxic hepatitis both in patients and animal models.To research the clinical manifestations of this disease and how to rescue the DMAc induced functional loss in patients.In

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