orixa japonica/alkaloid

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Pharmacological properties of pteleprenine, a quinoline alkaloid extracted from Orixa japonica, on guinea-pig ileum and canine left atrium.

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We have investigated the pharmacological properties of pteleprenine, a quinoline alkaloid, on contractile responses of the guinea-pig ileum and on inotropic responses of the canine left atrium. Although pteleprenine (0.1-1 microM) had no effect on the contraction of the ileum induced by

[Pharmacological properties of pteleprenine, a quinoline alkaloid from Orixa japonica (Rutaceae), in guinea pig ileum and canine left atrium].

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We investigated the pharmacological properties of pteleprenine, a quinoline alkaloid contained in the Rutaceous plant, Orixa japonica, on the contractile responses of the guinea pig ileum and on the inotropic responses of the canine left atrium. Contractile responses of the ileum to acetylcholine

Rat small intestine muscle relaxation alkaloids from Orixa japonica leaves.

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Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first

Quinolone alkaloids with nitric oxide production inhibitory activity from Orixa japonica.

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Four new quinolone alkaloids, orixalone A (1), B (2), C (3), and D (4), together with 12 known compounds were isolated from the stems of Orixa japonica. Orixalone A (1) inhibited nitric oxide production in murine macrophage-like RAW 264.7 cells stimulated with interferon-gamma and

New quinoline alkaloids from the leaves and stems of Orixa japonica, orijanone, isopteleflorine and 3'-O-methylorixine.

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Orixajaponica (Rutaceae) is a shrub widely distributed in Japan, and has been found to contain various quinoline alkaloids. We investigated the alkaloidal constituents of O. japonica, and four quinoline alkaloids were isolated and characterized. Three of these alkaloids are new natural products.

Bioactivities of a New Pyrrolidine Alkaloid from the Root Barks of Orixa japonica.

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A new pyrrolidine alkaloid named (Z)-3-(4-hydroxybenzylidene)-4-(4-hydroxyphenyl)-1-methylpyrrolidin-2-one was isolated from the ethanol extract of the root barks of Orixa japonica. The structure of the new alkaloid was elucidated on the basis of NMR and MS analysis. The compound exhibited

Alkaloids of root-bark of Orixa japonica Thumb. XII. Nuclear magnetic resonance study of N-methylorixidinine, N-methylisoorixidinine, and N-methylorixidine.

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Alkaloids of the root-bark of Orixa japonica Thunb. V. On the structure of Kokusagine.

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Alkaloids of the root-bark of Orixa japonica Thunb. XI. The structures of orixidine and orixidinine.

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