sepsis/fatigue

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[Lysozyme activity in fatigue and in experimental staphylococcal septicemia].

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Sepsis Alerts in Emergency Departments: A Systematic Review of Accuracy and Quality Measure Impact

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Introduction: For early detection of sepsis, automated systems within the electronic health record have evolved to alert emergency department (ED) personnel to the possibility of sepsis, and in some cases link them to suggested care

[Sepsis--clinical parameters of recognition and differentiation].

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BACKGROUND Even today, early recognition of sepsis remains a great problem, requiring the search for clinical symptoms and signs with predictive features. OBJECTIVE to define the number of days of disease till hospitalization and value of some clinical signs in recognition and differentiation of

A case of lobar pneumonia and sepsis with death caused by invasive Klebsiella rhinoscleromatis infection.

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Klebsiella pneumoniae often causes pneumonia and other infections in heavy drinkers and patients with diabetes. Pneumonia caused by Klebsiella rhinoscleromatis, a subspecies of K. pneumoniae, has not been previously reported. We report a case of pneumonia caused by K. rhinoscleromatis. A 68-year-old

A new treatment of sepsis caused by veillonella parvula: A case report and literature review.

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UNASSIGNED Veillonella parvula is usually regarded as a contaminant bacteria associated with polymicrobial infection. Here we report a rare case of sepsis caused by V. parvula, which was successfully treated by chloramphenicol. In addition, the therapeutic strategy for V. parvula infection was

Sepsis: stimulation of energy-dependent protein breakdown resulting in protein loss in skeletal muscle.

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Muscle catabolism is a characteristic metabolic response to sepsis, severe infection, and injury. In patients with severe and protracted sepsis, the catabolic response results in muscle wasting and fatigue, which may adversely affect the outcome in these patients. An understanding of the regulation

Beneficial effects of dantrolene on sepsis-induced diaphragmatic dysfunction are associated with downregulation of high-mobility group box 1 and calpain-caspase-3 proteolytic pathway.

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BACKGROUND Intracellular calcium overload is a major contributing factor to diaphragmatic dysfunction triggered by sepsis. In this study, the possible role of dantrolene, a ryanodine receptor inhibitor, in preventing the release of calcium from the sarcoplasmic reticulum in diaphragmatic dysfunction

Automated monitoring compared to standard care for the early detection of sepsis in critically ill patients.

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Sepsis is a life-threatening condition that is usually diagnosed when a patient has a suspected or documented infection, and meets two or more criteria for systemic inflammatory response syndrome (SIRS). The incidence of sepsis is higher among people admitted to critical care settings such as the

Testosterone improves muscle function of the extensor digitorum longus in rats with sepsis.

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Among patients with Intensive care unit-acquired weakness (ICUAW), skeletal muscle strength often decreases significantly. This study aimed to explore the effects of testosterone propionate on skeletal muscle using rat model of sepsis. Male SD rats were randomly divided into experimental group,

Association between the transcriptional levels of Htr-1a and tryptophan hydroxylase-1 in the hippocampus and the antifatigue effects of leucine on rats with postoperative fatigue.

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Leucine (Leu), a branched-chain amino acid (BCAA), is widely used in clinical practice following severe burns, gastrointestinal surgery, trauma and sepsis. In the present study, the antifatigue effects of BCAAs on a postoperative fatigue (POF) rat model, induced by 70% intestinal resection, were

ONO1714, a new inducible nitric oxide synthase inhibitor, attenuates sepsis-induced diaphragmatic dysfunction in hamsters.

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Sepsis causes impairment of diaphragmatic contractility and endurance capacity. Nitric oxide (NO) produced via inducible NO synthase (iNOS) has been implicated in the pathogenesis. Peroxynitrite, a NO-derived powerful oxidant, may be responsible for infection-induced diaphragmatic muscle failure.

Lidocaine attenuates sepsis-induced diaphragmatic dysfunction in hamsters.

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OBJECTIVE Sepsis or endotoxemia causes diaphragmatic dysfunction, which may contribute to respiratory distress. Toxic free radicals are partly responsible for the pathogenesis. Lidocaine scavenges the reactive molecules. The purpose of the current study was to examine whether lidocaine prevents the

Amino acid metabolism, muscular fatigue and muscle wasting. Speculations on adaptations at high altitude.

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Recent investigations from our and other laboratories indicate that glycogen is a carbon-chain precursor in muscle for the synthesis of TCA cycle intermediates and glutamine. During intense exercise and in conditions of a relative lack of energy (hypoxia, trauma, sepsis) the metabolism of

G-CSF stimulated donor granulocyte collections for neutropenic sepsis.

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Granulocyte transfusions may be beneficial in neutropenic patients with progressive infections despite appropriate antibiotics. In order to evaluate both the feasibility of granulocyte collection in normal donors receiving granulocyte colony-stimulating factor (G-CSF) and the efficacy of infusing

[A case of prostate abscess with sepsis, infectious endocarditis and pyogenic spondylitis].

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A 65-year-old man with diabetes mellitus (DM) presented with an indwelling urethral catheter placed for urinary retention by his previous doctor. Thereafter, he had fever, vomiting and general fatigue. His blood examination showed severe inflammatory findings. He was diagnosed with acute prostatitis

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