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Forty cases were examined by a new lymphoscintigraphic approach using intradermal injections of Tc-99m human serum albumin (HSA). Thirty-three patients had lymphedema due to the metastases of a malignant tumor and/or the dissection of lymph nodes. The others were control patients without lymphedema.
Lymphscintigraphy using Tc-99m human serum albumin (HSA) was examined in 23 patients with peripheral leg lymphedema. Each was injected intradermally with one mCi in the medial web space bilaterally. Images of the lower pelvis and both thighs were obtained within five minutes after injection using an
BACKGROUND
Lymphoscintigraphy has often been used for evaluating arm lymphatic dysfunction, but no optimal approach for quantification has so far emerged. We propose a quantifiable measure of lymphatic function that we applied in patients treated for breast cancer.
METHODS
Eleven patients, aged
Edema of the lower extremities is a difficult clinical problem. It can be due to stasis, obstruction of the lymphatic channels, increased production of lymph beyond the drainage capacity of the lymphatic vessels. It is often difficult to differentiate between these varieties. Lymphoscintigraphy was
A cream, Unguentum lymphaticum, which has been shown to be effective (clinically and experimentally) in lymphedema, was tested in dextran and burn edemas and acute lymphedema in rats. It was very effective indeed in lymphedema, completely preventing the 36% increase in the volumes of the legs found
Dynamic imaging of lymphatic flow was performed in 23 patients complaining of lymphedema of the lower extremities. All were injected intradermally with 1 mCi of Tc-99m human serum albumin (HSA) in the medial web on the dorsum of both feet. Image acquisition for the lower pelvis and both thighs was
BACKGROUND
Our objective was to develop an animal model of postsurgical lymphedema that would permit quantitation of edema and lymphatic function after the removal of a single popliteal lymph node in sheep.
METHODS
As a measure of lymph transport, (125)I-human serum albumin was injected into
OBJECTIVE
The aim of this study was to evaluate the effect of implementing a new technique, intradermal injection lymphoscintigraphy, at rest and after muscular exercise on the functional assessment of the lymphatic system in a group of patients with delayed or absent lymph drainage.
METHODS
We
Primary intestinal lymphangiectasia is an unusual cause of protein losing enteropathy due to either congenital malformation or obstruction of lymphatics of intestine. The disease can affect all or only a small part of the small intestine. Peripheral lymphedema may be associated. The diagnosis is
BACKGROUND
The authors' objective was to test whether the transplantation of an autologous lymph node into a nodal excision site in sheep would restore lymphatic transport function and reduce the magnitude of postsurgical lymphedema.
METHODS
As a measure of lymph transport, iodine-125 human serum
The concentration of cholesterol, apolipoproteins A-I, B, and E has been determined in lymphedema fluid from nine patients with chronic primary lymphedema. The concentrations were: 38.14 +/- 21.06 mg/dl for cholesterol, 15.6 +/- 6.17 mg/dl for apolipoprotein A-I, 7.5 +/- 2.8 mg/dl for apolipoprotein
OBJECTIVE
Lymphoscintigraphy is currently the leading diagnostic modality of lower extremity lymphoedema but has been criticized for being unreliable. Washout rate constants have been investigated and proven to be of diagnostic value in several studies of breast-cancer-related lymphoedema; however,