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balkan nephropathy/phosphatase

Veza se sprema u međuspremnik
ČlanciKlinička ispitivanjaPatenti
5 rezultatima
Protein phosphatase magnesium-dependent-1A (PPM1A) dephosphorylates SMAD2/3, which suppresses TGF-β signaling in keratinocytes and during Xenopus development; however, potential involvement of PPM1A in chronic kidney disease is unknown. PPM1A expression was dramatically decreased in the

[Endemic Balkan nephropathy (author's transl)].

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Prijava Registriraj se
Endemic Balkan nephropathy (EBN) is a chronic interstitial nephritis which may occur at any age and may affect several members of the same family. The condition is slowly progressive and can more easily be diagnosed in its advanced than in its early stages. Early symptoms include severe anaemia and

[One-year follow-up of renal function in endemic nephropathy families].

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Prijava Registriraj se
BACKGROUND Endemic nephropathy is familial, chronic tubulointerstitial disease with an insidious onset and asymptomatic, slow progressive course. OBJECTIVE The present study was undertaken with the aim to find out whether new persons with renal disorders can be detected among members of endemic

Evaluation of criteria for the diagnosis of Balkan endemic nephropathy.

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Prijava Registriraj se
BACKGROUND The diagnosis of Balkan endemic nephropathy (BEN) is often made using Danilovic's criteria. The aim of this study was to determine the prevalence, sensitivity, specificity, and predictive value of Danilovic's criteria and several additional indices. METHODS The study included 19 BEN
PPM1A and PTEN emerged as novel suppressors of chronic kidney disease (CKD). Since loss of PPM1A and PTEN in the tubulointerstitium promotes fibrogenesis, defining molecular events underlying PPM1A/PTEN deregulation is necessary to develop expression rescue as novel therapeutic strategies. Here we
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