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panaxynol/ג ינסנג

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
עמוד 1 מ 30 תוצאות

Panaxynol induces neurite outgrowth in PC12D cells via cAMP- and MAP kinase-dependent mechanisms.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Panaxynol, a polyacetylene ((3R)-heptadeca-1,9-diene-4,6-diyn-3-ol; syn. falcarinol), was isolated from the lipophilic fractions of Panax notoginseng, a Chinese traditional medicinal plant. In the present study, we reported the neurotrophic effects of panaxynol on PC12D cells and mechanism involved

Up-regulation of M1 muscarinic receptors expressed in CHOm1 cells by panaxynol via cAMP pathway.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Loss of cholinergic neurons along with muscarinic acetylcholine receptors (mAChRs) in cerebral cortex and hippocampus is closely associated with Alzheimer's disease (AD). Recent drug development for AD treatment focuses heavily on identifying M(1) receptor agonists. However, mAChRs undergo

Induction of apoptosis in human promyelocytic leukemia HL60 cells by panaxynol and panaxydol.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Panaxynol and panaxydol are naturally occurring polyacetylenes, isolated from the lipophilic fractions of Panax notoginseng, that exert anti-proliferative effects against malignant cells. However, to the best of our knowledge, no study concerning the inhibitory effects of the two polyacetylenes on

Protective Effect of Panaxynol Isolated from Panax vietnamensis against Cisplatin-Induced Renal Damage: In Vitro and In Vivo Studies.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Polyacetylenic compounds isolated from Panax species are comprised of non-polar C17 compounds, exhibiting anti-inflammatory, antitumor, and antifungal activities. Panaxynol represents the major component of the essential oils of ginseng. We investigated whether panaxynol isolated from

[Simultaneous determination of panaxynol and panaxydol in fibrous root of Panax ginseng by HPLC].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
OBJECTIVE To establish an HPLC method for simultaneous determination of panaxynol and panaxydol from the fibrous root of Panax ginseng. METHODS The analysis was performed on Elite C18 column (4.6 mm x 150 mm, 5 microm) with mobile phase gradient of CH3CN-water at a flow rate of 1.0 mL x min(-1). The

Antiplatelet actions of panaxynol and ginsenosides isolated from ginseng.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The antiplatelet effect of panaxynol isolated from the diethyl ether layer was compared with those of ginsenosides from the butanol layer of Panax ginseng. Panaxynol (0.1 mg/ml) inhibited markedly the aggregation of washed platelets induced by collagen, arachidonic acid, ADP, ionophore A23187, PAF

Biosynthesis of panaxynol and panaxydol in Panax ginseng.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The natural formation of the bioactive C17-polyacetylenes (-)-(R)-panaxynol and panaxydol was analyzed by 13C-labeling experiments. For this purpose, plants of Panax ginseng were supplied with 13CO2 under field conditions or, alternatively, sterile root cultures of P. ginseng were supplemented with

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Ulcerative colitis has a significant impact on the quality of life for the patients, and can substantially increase the risk of colon cancer in patients suffering long-term. Conventional treatments provide only modest relief paired with a high risk of side effects, while complementary and
BACKGROUND American ginseng is capable of ameliorating cardiac dysfunction and activating Nrf2, a master regulator of antioxidant defense, in the heart. This study was designed to isolate compounds from American ginseng and to determine those responsible for the Nrf2-mediated resolution of inflamed

Antitrypanosomal properties of Panax ginseng C. A. Meyer: new possibilities for a remarkable traditional drug.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
African trypanosomiasis is still a major health problem in many sub-Saharan countries in Africa. We investigated the effects of three preparations of Panax ginseng, Panax notoginseng, isolated ginsenosides, and the polyacetylene panaxynol on Trypanosoma brucei brucei and the human cancer cell line

Effect of petroleum ether extract of Panax ginseng roots on proliferation and cell cycle progression of human renal cell carcinoma cells.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Panax ginseng roots have long been used as a medicinal herb in oriental countries. We have investigated anti-proliferative effects of lipid soluble Panax ginseng components on human renal cancer cell lines. Petroleum ether extract of Panax ginseng roots (GX-PE) or its partially purified preparation

Antiplatelet components in Panax ginseng.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Panaxynol and ginsenosides Ro, Rg1, and Rg2 were found to be the main antiplatelet components in the diethyl ether and 1-butanol fractions, respectively, during the activity-guided fractionation of Panax ginseng, Panaxynol inhibited the aggregation, release reaction, and thromboxane formation in
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