anxiolytic/脳卒中

OBJECTIVE The main objective of our study was to detail the frequency and clinical determinants of poststroke generalized anxiety disorders in a large, well-defined stroke cohort. METHODS A total of 277 stroke patients aged 55-85 were subjected to a comprehensive psychiatric evaluation between 3 and

BACKGROUND Cyclic nucleotide Phosphodiesterases (PDEs) are ubiquitously distributed in mammalian tissues and play a major role in cell signaling by hydrolyzing cyclic Adenosine Monophosphate (cAMP) and cyclic Guanosine Monophosphate (cGMP). Impairments in signal transduction have been implicated as

The anxiolytic effects of aniracetam have not been proven in animals despite its clinical usefulness for post-stroke anxiety. This study, therefore, aimed to characterize the anxiolytic effects of aniracetam in different anxiety models using mice and to examine the mode of action. In a social

This article reviews randomized control trials (RCT's) published in 2006 of various medications evaluated for stroke patients. These trials were primarily efficacy studies. These included aggrenox (an antiplatelet agent), magnesium (to treat arterial spasm after an aneurysmal subarachnoid

BACKGROUND The use of antithrombotic drugs (anticoagulants and antiplatelet drugs) has been reported to increase the risk of hemorrhagic stroke (HS) relative to no treatment. This study was performed to characterize the incidence and predictors of HS in users of acetylsalicylic acid (ASA) for the

OBJECTIVE Among methods of complementary treatment of depression, massage plays an important role, at least in the U.S.A. Although there are some pointers to the antidepressive and anxiolytic action of slow-stroke massage in various randoms studies of patient cohorts, there have been no controlled

BACKGROUND Patients with dementia may be at a higher risk for death from stroke. We aimed to describe characteristics of dementia patients that died from ischemic stroke (IS) in Sweden. METHODS A retrospective longitudinal analysis of prospectively collected data of patients registered into the

Diabetes and anxiety disorders are independent risk factors for stroke. However, it remains unclear whether the risk of stroke is higher among diabetic patients with comorbid anxiety than without comorbid anxiety. Therefore, the purpose of this study was to investigate the association between

OBJECTIVE To investigate whether of anxiety-related blood pressure (BP) variability can be corrected in patients with atrial fibrillation (AF) who have experienced cardioembolic stroke (CES). METHODS The investigation enrolled 125 patients (mean age, 68.5±5.7 years) with AF, who had experienced CES.

The use of psychopharmacology for stroke patients requires careful attention to diagnosis, selection of medications for a particular use and avoidance of specific actions that interfere with recovery and function, and careful monitoring for results and side effects. Any given psychotropic medication

Post-stroke depression is a serious complication of ischemic stroke which has negative influences on patients' quality of life and on recovery from symptoms and the prognosis of the underlying disease. We report here a study of the efficacy of treatment of patients with post-stroke depression with

Post-stroke depression is a serious complication of ischemic stroke that exerts a negative effect on patient's quality of life, restoration of symptoms and prognosis. The study of efficacy of the drug opra (citalopram) in the treatment of post-stroke depression revealed the improvement in 93.3% of

The objective was to compare the prevalence of sleep apnea syndrome (SAS) in elderly individuals with a history of stroke to the one in individuals, matched by age and sex with a history of insomnia. To determine if previous subjective sleep complaints in the elderly are associated with stroke. A

In a study of 90 patients with post-stroke depression the Hamilton Depression Scale was used together with a clinical psychopathological study. One group of patients was treated with amitriptyline, another with minor tranquilizers (seduxen), and the third (controls) received neither antidepressants,

7-Bromo-5-(2-chlorophenyl)-2,3-dihydro-2-(methoxymethyl)-1H-1,4- benzodiazepine X HCl (metaclazepam, KC-2547, Ka-2547, Talis) is a novel 1,4-benzodiazepine characterized by a high selectivity of its anxiolytic effects. The present experiments were performed to contribute to its general