Circulation: Arrhythmia and Electrophysiology 2019-Oct
Outcomes of Atrial Fibrillation Ablation in Morbidly Obese Patients Following Bariatric Surgery Compared With a Nonobese Cohort.
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METHODS
This was a single-center observational cohort study. We matched 51 morbidly obese patients [body mass index ≥40 kg/m2] who had undergone prior BS in a 2:1 manner with 102 nonobese patients and 102 morbidly obese patients without prior BS on the basis of age, sex, and timing of atrial fibrillation ablation. Our primary outcome of interest was arrhythmia recurrence.RESULTS
From the time of BS to ablation, BS was associated with a significant reduction in body mass index (47.6±9.3 to 36.7±7; P<0.0001), glycated hemoglobin (6.7±1.5 to 5.8±0.6; P<0.0001), and systolic blood pressure (145±13 to 118±11; P<0.0001). During a mean follow-up of 29±13 months following ablation, recurrent arrhythmia occurred in 10/51 (20%) patients in the BS group compared with 25/102 (24.5%) patients in the nonobese group and 56 (55%) patients in the non-BS morbidly obese group (P<0.0001). No procedural complications were observed in the BS group.