inert gas narcosis/crise epiléptica

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Lithium effects: protection against nitrogen narcosis, potentiation of HPNS.

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The effect of either 10, 8, or 6 meq/kg of intraperitoneal lithium chloride or sodium chloride on the loss of righting response (RR50) produced by 18.2 ATA N2-ATA O2 was examined in rats. Results were compared to the effects of 10, 8, 6, or 4 meq/kg of intraperitoneal lithium chloride given 24 h

Effects of prolonged simultaneous exposure of CD-1 mice to high pressures and inert gas narcosis.

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Addition of N2 to the heliox used in pressure conditioning exposures reduces or suppresses the increase in convulsion threshold pressure (Pc) as well as the change in compression rate effect resulting from pressure exposures in the absence of N2; 18 atm N2 neutralizes the effect of 80 ATA total

Inert gas narcosis, the high pressure neurological syndrome, and the critical volume hypothesis.

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The hypothesis that general anesthesia or pressure-induced convulsions occur when a hydrophobic region is expanded or compressed, respectively, by critical amounts is consistent with recent data obtained with mice. Calculations show that anesthesia occurs at an expansion of 1.1 percent and

Neurological oxygen toxicity.

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SCUBA diving has several risks associated with it from breathing air under pressure--nitrogen narcosis, barotrauma and decompression sickness (the bends). Trimix SCUBA diving involves regulating mixtures of nitrogen, oxygen and helium in an attempt to overcome the risks of narcosis and decompression

Epilepsy and recreational scuba diving: an absolute contraindication or can there be exceptions? A call for discussion.

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Recreational scuba diving is a popular sport, and people with epilepsy often ask physicians whether they may engage in diving. Scuba diving is not, however, without risk for anyone; apart from the risk of drowning, the main physiological problems, caused by exposure to gases at depth, are

The opposing physiological effects of high pressures and inert gases.

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The physiological effects on mammals of elevated pressures (approximately 100 atmospheres) must be considered in the context of the inert gases breathed. The most striking effect of pressure per se is a central hyperexcitability manifest at first by trembling of the entremities and finally by

Low susceptibility to inert gases and pressure symptoms in TREK-1-deficient mice.

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Nervous disorders may occur after an organism is saturated with inert gases, which may alter the lipid bilayer structure, according to their liposolubility coefficient. Increase in the nitrogen partial pressure induces a neurological syndrome called 'nitrogen narcosis'. By contrast, high pressures

Compressed breathing air - the potential for evil from within.

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Human underwater activities rely on an adequate supply of breathable compressed gas, usually air, free from contaminants that could cause incapacitation underwater or post-dive or longer-term health effects. Potentially fatal but well-known hazards are hypoxia secondary to steel cylinder corrosion

The interactions between pressure and anaesthetics.

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Compression of animals causes excitation, which has recently posed a barrier to deeper diving. The broad question addressed here is how far the inert gas breathed modifies the excitatory effects of hydrostatic pressure. By using aquatic animals we first show that helium postpones the onset of

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