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Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND Bitter taste receptors (T2R) have recently been demonstrated to contribute to sinonasal innate immunity. One T2R, T2R38, regulates mucosal defense against gram-negative organisms through nitric oxide (NO) production, which enhances mucociliary clearance and directly kills bacteria. To

Alloscardovia omnicolens gen. nov., sp. nov., from human clinical samples.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
The taxonomic position of 12 isolates tentatively assigned to the genus Bifidobacterium on the basis of a limited phenotypic characterization was examined. The isolates were collected between 1978 and 2005 in Belgium, Sweden and Norway, and originated from various human clinical samples, including

Isolation and immunobiological classification of Streptococcus sanguis from human tooth surfaces.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
A total of 113 pure cultures of Streptococcus sanguis were obtained from dental plaque samples of 64 subjects. All isolates synthesized glucan from sucrose, elaborated peroxide, and were alpha-hemolytic. Two biotypes and four serotypes were differentiated within the species. Biotype A (95 isolates)

Dual binding mode of "bitter sugars" to their human bitter taste receptor target.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
The 25 human bitter taste receptors (hTAS2Rs) are responsible for detecting bitter molecules present in food, and they also play several physiological and pathological roles in extraoral compartments. Therefore, understanding their ligand specificity is important both for food research and for

"Tasting" the cerebrospinal fluid: Another function of the choroid plexus?

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
The choroid plexus (CP) located in brain ventricles, by forming the interface between the blood and the cerebrospinal fluid (CSF) is in a privileged position to monitor the composition of these body fluids. Yet, the mechanisms involved in this surveillance system remain to be identified. The taste
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