elaeis/neoplasms

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Isolation and characterization of an oil palm constitutive promoter derived from a translationally control tumor protein (TCTP) gene.

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We have characterized an oil palm (Elaeis guineensis Jacq.) constitutive promoter that is derived from a translationally control tumor protein (TCTP) gene. The TCTP promoter was fused transcriptionally with the gusA reporter gene and transferred to monocot and dicot systems in order to study its

Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells.

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BACKGROUND Tocomin® represents commercially available mixture of naturally occurring tocotrienols (T3s) and tocopherols extracted from palm oil/palm fruits that possess powerful antioxidant, anticancer, neuro/cardioprotective and cholesterol-lowering properties. Cellular autophagy represents a

Oil palm phenolics (OPP) inhibit pancreatic cancer cell proliferation via suppression of NF-κB pathway.

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BACKGROUND Oil palm phenolics (OPP) or Palm Juice (PJ), a water soluble extract from the palm fruit (Elaies guineensis) has been documented to have anti-carcinogenic activities in various cancer types. METHODS To investigate OPP effects in pancreatic cancer (PaCa) cells, two PaCa cell lines (PANC-1

Gene expression changes in spleens and livers of tumour-bearing mice suggest delayed inflammation and attenuated cachexia in response to oil palm phenolics.

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OBJECTIVE Plant phenolics can inhibit, retard or reverse carcinogenesis, and may thus help prevent or treat cancer. Oil palm phenolics (OPP) previously showed anti-tumour activities in vivo via a cytostatic mechanism at 1,500 ppm gallic acid equivalent. Here, we report other possible molecular

Isolation and expression analysis of genes encoding MET, CMT, and DRM methyltransferases in oil palm (Elaeis guineensis Jacq.) in relation to the 'mantled' somaclonal variation.

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In oil palm (Elaeis guineensis Jacq.), approximately 5% of somatic embryo-derived regenerants show homeotic changes during floral development, involving an apparent feminization of male parts in flowers of both sexes, called the 'mantled' phenotype. This variant phenotype is associated with a

Aflatoxin load of common food in savanna and forest regions of Nigeria.

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Aflatoxin, one of the most widespread of the known carcinogens, is present at a high level in most common foods stored poorly for long periods in Nigeria. It may work synergistically with other carcinogens to produce the high incidence of primary liver cancer seen in young men under the age of 40.

Biocompatible oil core nanocapsules as potential co-carriers of paclitaxel and fluorescent markers: preparation, characterization, and bioimaging.

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The present work is focused on the long-term stability and in vitro cellular internalization of newly designed biocompatible polyester nanocapsules prepared via nanoprecipitation approach with mean diameter <165 nm and narrow size distribution, dedicated to theranostic applications. We monitored the

Comparison of olive leaf, olive oil, palm oil, and omega-3 oil in acute kidney injury induced by sepsis in rats.

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Hypotension, increased production of reactive oxygen species, and inflammation are all observed in experimental models of sepsis induced by lipopolysaccharide (LPS).The aim of this study was to evaluate the effects of an ethanolic extract of Brazilian olive

The Pharmacological Potential of Oil Palm Phenolics (OPP) Individual Components.

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The oil palm tree (Elaeis guineensis) from the family Arecaceae is a high oil-producing agricultural crop. A significant amount of vegetation liquor is discarded during the palm oil milling process amounting to 90 million tons per year around the world. This water-soluble extract is rich in

Cytotoxicity of methanol extracts of Elaeis guineensis on MCF-7 and Vero cell lines.

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OBJECTIVE To investigate the cytotoxic effect of Elaeis guineensis methanol extract on MCF-7 and Vero cell. METHODS In vitro cytotoxicity was evaluated in by MTT assay. Cell morphological changes were observed by using light microscope. RESULTS The MTT assay indicated that methanol extract of the

Differential transcriptomic profiles effected by oil palm phenolics indicate novel health outcomes.

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BACKGROUND Plant phenolics are important nutritional antioxidants which could aid in overcoming chronic diseases such as cardiovascular disease and cancer, two leading causes of death in the world. The oil palm (Elaeis guineensis) is a rich source of water-soluble phenolics which have high

Positive outcomes of oil palm phenolics on degenerative diseases in animal models.

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It is well established that plant phenolics elicit various biological activities, with positive effects on health. Palm oil production results in large volumes of aqueous by-products containing phenolics. In the present study, we describe the effects of oil palm phenolics (OPP) on several

Surface-modified nanocrystalline cellulose from oil palm empty fruit bunch for effective binding of curcumin.

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Rod-shape particles have been a good drug carrier due to the long circulatory time, tumor accumulation and high cellular uptake in body. Acid-hydrolysed nanocrystalline cellulose (NCC) from empty fruit bunch exhibited a width of 13-30nm and a length of 150-360nm in rod-shape structure. NCC holds

Phytonutrient deficiency: the place of palm fruit.

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The oil palm (Elaeis guineensis) is native to many West African countries, where local populations have used its oil for culinary and other purposes. Large-scale plantations, established principally in tropical regions (Asia, Africa and Latin America), are mostly aimed at the production of oil,

Effect of red palm oil on some hepatic drug-metabolizing enzymes in rats.

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Red palm oil (RPO) from Elaeis guineensis is being considered for use as an edible oil in India as it is one of the richest natural sources of carotenoids. The effect of RPO on the host detoxification system, which is a vital mechanism in cancer prevention, was studied in three separate batches of

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