testosterone/carie dentară

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The role of testosterone in the nasal cavity tumors induced by N-nitrosobis(2-oxopropyl)amine in rats.

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In a previous study in rats we have shown that castration prior to weekly administration of N-nitrosobis(2-oxopropyl)amine (BOP) prevents induction of nasal and paranasal cavity (NPNC) tumors, indicating androgen dependency of these neoplasms. To investigate the possible inhibitory effect of

Experimental dental caries. VIII. Effect of thyroid-testosterone administration on dental caries in rat.

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[Effect of thyroid and testosterone administration on dental caries in the rat].

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[Effect of progesterone and testosterone on the concentration of lipids in the fluid of uterine cavity in rats].

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Testosterone complex and non-steroidal ligands of human aromatase.

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Cytochrome P450 aromatase (AROM) catalyzes the biosynthesis of estrogen from androgen. Previously crystal structures of human AROM in complex with the substrate androstenedione, and inhibitors exemestane, as well as the newly designed steroidal compounds, have been reported. Here we report the first

Lower prevalence of non-cavity-distorting uterine fibroids in patients with polycystic ovary syndrome than in those with unexplained infertility.

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To study whether there is a difference in the prevalence of non-cavity-distorting uterine fibroids between infertile patients with polycystic ovary syndrome (PCOS) and those with unexplained infertility (UI).A secondary analysis of data from three

Potential repositioning of GV1001 as a therapeutic agent for testosterone‑induced benign prostatic hyperplasia.

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Benign prostatic hyperplasia (BPH) is one of the leading causes of male reproductive disorders. Therapeutic agents currently in use have severe side effects; therefore, alternative drugs that exhibit improved therapeutic activity without side effects are required. The present study investigated the

Intratesticular testosterone concentration following intratunical administration in the hypogonadal animal.

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The serum and intratesticular testosterone concentration (ITC) after testosterone administration in the tunica vaginalis (TV) sac compared to parenteral administration was studied in 20 dogs that were rendered hypogonadal by gonadotropin-releasing hormone antagonist ('Nal-Glu' GnRH antagonist) in a

Stimulation of Spermatogenesis and Synthesis of Testosterone by Allotransplantation of Neonatal Testicular Tissue under Tunica Albuginea of Cryptorchid Testis.

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The abdominal type of cryptorchism was modeled on random-bred albino rats by replacing both testes from the scrotum into the abdominal cavity for 3 weeks; thereupon they were manipulated into the scrotum. In control rats, no additional surgery was performed. In experimental rats, the testicular

17beta-estradiol combined with testosterone promotes chicken osteoblast proliferation and differentiation by accelerating the cell cycle and inhibiting apoptosis in vitro.

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Medullary bone is a unique tissue in the long bones cavities of lay hens, and plays an important role as a calcium reservoir for egg-shell formation. Medullary bone formation requires the synergistic action of estrogen and androgen on osteoblasts during the early stage of sexual maturity. The

Testimony of the correlation between DHEA and bioavailable testosterone using a biochromatographic concept: effect of two salts.

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In a previous paper (C. André et al., submitted to J. Chromatogr. B) a mathematical model based on the Langmuir theory was developed to visualize the competition effect between testosterone and deshydroepiandrosterone (DHEA) for their identical human serum albumin (HSA) binding cavity. In this work,

Testosterone restores testicular inhibin content in cryptorchid rats.

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The effects of testosterone administration on testicular inhibin content and histology were studied in bilaterally cryptorchid rats, in which a marked decrease in testicular inhibin content had been observed. Mature male Wistar rats weighing approximately 300 g were made bilaterally cryptorchid by

Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.

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BACKGROUND Mammalian 3 alpha-hydroxysteroid dehydrogenases (3 alpha-HSDs) modulate the activities of steroid hormones by reversibly reducing their C3 ketone groups. In steroid target tissues, 3 alpha-HSDs act on 5 alpha-dihydrotestosterone, a potent male sex hormone (androgen) implicated in benign

A multi-institutional observational study of testosterone levels after testosterone pellet (Testopel(®)) insertion.

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BACKGROUND Implantable testosterone pellets were approved by the Food and Drug Administration in 1972 for the treatment of testosterone deficiency syndrome (TDS). Clinical use of this testosterone delivery modality has been limited until its recent reintroduction (Testopel(®) , Slate

Molecular modelling and site-directed mutagenesis on a bovine anti-testosterone monoclonal antibody.

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A three-dimensional (3D) molecular model of the antigen-combining site of a bovine anti-testosterone monoclonal antibody has been constructed. In the model, the CDRs, and a single heavy chain framework region residue (Trp47), associate to form a hydrophobic cavity large enough to accommodate a

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