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Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
Hali
Wadhamini
Lamis Kaddam

Maneno muhimu

Kikemikali

To assess the effects on hormonal and metabolic changes in the PCOs patients after ingestion of Arabic gum

Maelezo

Polycystic ovary syndrome (PCOS) affects 5-20% of women of reproductive age worldwide it increases the risk for type 2 diabetes mellitus, cerebrovascular and cardiovascular events and not to mention it is one of the main causes of infertility. in the management of PCOS life style modification like weight reduction is necessary and recently it was discovered that GA ingestion causes significant reduction in BMI and body fat percentage among healthy adult females.so if GA could also affect the hormones and the metabolic changes in PCOs is going to be useful in decreasing the comorbidities and even treating PCOs.

Tarehe

Imethibitishwa Mwisho: 12/31/2019
Iliyowasilishwa Kwanza: 12/24/2019
Uandikishaji uliokadiriwa Uliwasilishwa: 12/28/2019
Iliyotumwa Kwanza: 01/01/2020
Sasisho la Mwisho Liliwasilishwa: 01/21/2020
Sasisho la Mwisho Lilichapishwa: 01/22/2020
Tarehe halisi ya kuanza kwa masomo: 01/24/2020
Tarehe ya Kukamilisha Msingi iliyokadiriwa: 04/14/2020
Tarehe ya Kukamilisha Utafiti: 06/14/2020

Hali au ugonjwa

Polycystic Ovary Syndrome

Uingiliaji / matibabu

Dietary Supplement: Intervention Group

Dietary Supplement: Control group

Awamu

-

Vikundi vya Arm

MkonoUingiliaji / matibabu
Experimental: Intervention Group
This arm will receive 100% natural Gum Arabic provided in a powder form as 30-grams-dose for 12 weeks
Dietary Supplement: Intervention Group
Oral Digestion of Gum Arabic dissolved in 200 ml of water to be consumed early morning in daily basis for 12 weeks
Placebo Comparator: Control group
This group will be provided with pectin powder provided as two-gram-dose fo
Dietary Supplement: Control group
Oral Digestion of Pectin to be consumed early morning in daily basis for 12 weeks

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza 18 Years Kwa 18 Years
Jinsia Inastahiki KujifunzaFemale
Hupokea Wajitolea wa AfyaNdio
Vigezo

Inclusion Criteria:

- Patients who are diagnosed with PCO by independent Gynecologist

Exclusion Criteria:

- Diabetic patients

- Menopausal women

- History of allergy to Gum Arabic

Matokeo

Hatua za Matokeo ya Msingi

1. hormonal changes [12 weeks]

Measure changes from the baseline values regarding LH, FSH, and testosterone level

Hatua za Matokeo ya Sekondari

1. Metabolic change Serum cholestrol [12 weeks]

Measure decrease from the baseline values regarding serum cholesterol level

2. Metabolic change HBA1C [12 weeks]

Measure decrease from the baseline values regarding HBA1c

3. Body Mass index [12 weeks]

Measure decrease from the baseline values regarding BMI

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